Collaborating with MilliporeSigma to incorporate CCS values

Accurate screening for extractables and leachables (E&Ls) is imperative for consumer safety, no matter the product. Be it a pharmaceutical, an item of food packaging, or a medical device, consumers place their trust in manufacturers to protect them from the thousands of potentially harmful chemicals that can leach into their products.

A new CCS calibration methodology and how it benefits the TWIMS community

We spoke with Brandon Ruotolo, Professor of Chemistry at the University of Michigan, and Keith Richardson, Principal Research Scientist at Waters, about their collaboration on a newly developed calibration approach and what it means for the future of travelling wave ion mobility spectrometry (TWIMS).

Introducing CCSondemand and the power of machine learning for CCS prediction

Collision cross section (CCS) values have long been established as a complementary identification metric that can aid the characterization of complex samples. In this blog post, Waters scientists, Mike McCullagh and Russell Mortishire-Smith discuss the fundamentals of CCS prediction and the exciting potential of the CCSondemand software.

Unlocking the power of DESI with IMS on the SYNAPT XS

Some ionization techniques involve significant sample preparation, taking valuable time away from scientific researchers. Desorption electrospray ionization (DESI) was developed by Graham Cooks’ group at Purdue University in 2004 as a mass spectrometry (MS) ionization method that does not require significant sample preparation and creates high throughputs.

Mapping the pathway of DIA innovation, from DDA to the SYNAPT XS

Evolving customer requirements have driven Waters’ innovation in data independent acquisition over 20 years. Fueled by the needs of our customers, Waters’ legacy spans the commercialization of data dependent acquisition to the development of our pioneering DIA technologies, including MSE, HDMSE and SONAR. The latest advances are now available side-by-side on the SYNAPT XS.

Pushing the boundaries of space exploration with IMS-MS

International Space Day is observed annually on the first Friday in May, and is dedicated to the extraordinary achievements, benefits and opportunities within space exploration. In celebration of International Space Day this year, we hope to inspire the next generation of scientists with some of the remarkable contributions mass spectrometry (MS) and ion mobility technology have made to furthering our understanding of outer space. Find out more in our latest blog post.
Just what we needed! Some really great talks here that I have been checking out this morning over coffee. For new students joining IM labs, I think the IM fundamentals talks by @ErinBakerNCSU & @bushresearch are an excellent resource.

History of Mass Spectrometry in Manchester – British Science Week

In honour of British Science week, we are going back to our roots to explore the rich heritage of MS in Manchester. Read on to discover the fascinating journey that has brought this technology to the modern age and the remarkable discoveries that have been made along the way…
Join the on-demand IMS Great Minds Summit 2020! Awesome talks from @ErinBakerNCSU , @MattBushSeattle , @RuotoloLab, @PerditaB & more. Covering fundamentals in IMS-MS & ground-breaking research. Are you ready to binge watch now and #SayYEStoIMS ?

Exploring Arctic biodiversity
with IMS

Today, the 22nd April, we celebrate Earth Day. Earth Day is a time to celebrate our planet’s rich biodiversity and highlight the importance of unique environments. In our latest blog post, Dr. Espen Hansen (pictured above) describes how the sustainable utilization of our planet’s biological resources is more important now than ever.
Join us on Facebook Live for STEM Live: The Science of What's Possible for Kids starting April 8th. Waters scientists will bring experiments for kids of all ages into your home laboratories! Learn more here:

Identifying allergens in springtime treats

The decoration of eggs for springtime celebrations is an activity that can bring joy and life into a household. For many, it can conjure up memories of baskets full of sweet goodies and egg hunts through the woods in springtime. However, spring can bring with it a number of allergy symptoms

IMS-MS increases information content in metabolomics studies

Metabolomics is a term applied to the global metabolite profiling of biological samples (particularly biofluids such as urine and plasma). It is combined with multivariate statistical analysis in order to identify changes in response to a toxic insult, disease progression or genetic modification…