A new CCS calibration methodology and how it benefits the TWIMS community

We spoke with Brandon Ruotolo, Professor of Chemistry at the University of Michigan, and Keith Richardson, Principal Research Scientist at Waters, about their collaboration on a newly developed calibration approach and what it means for the future of travelling wave ion mobility spectrometry (TWIMS).

Introducing CCSondemand and the power of machine learning for CCS prediction

Collision cross section (CCS) values have long been established as a complementary identification metric that can aid the characterization of complex samples. In this blog post, Waters scientists, Mike McCullagh and Russell Mortishire-Smith discuss the fundamentals of CCS prediction and the exciting potential of the CCSondemand software.

Unlocking the power of DESI with IMS on the SYNAPT XS

Some ionization techniques involve significant sample preparation, taking valuable time away from scientific researchers. Desorption electrospray ionization (DESI) was developed by Graham Cooks’ group at Purdue University in 2004 as a mass spectrometry (MS) ionization method that does not require significant sample preparation and creates high throughputs.

Mapping the pathway of DIA innovation, from DDA to the SYNAPT XS

Evolving customer requirements have driven Waters’ innovation in data independent acquisition over 20 years. Fueled by the needs of our customers, Waters’ legacy spans the commercialization of data dependent acquisition to the development of our pioneering DIA technologies, including MSE, HDMSE and SONAR. The latest advances are now available side-by-side on the SYNAPT XS.

Pushing the boundaries of space exploration with IMS-MS

International Space Day is observed annually on the first Friday in May, and is dedicated to the extraordinary achievements, benefits and opportunities within space exploration. In celebration of International Space Day this year, we hope to inspire the next generation of scientists with some of the remarkable contributions mass spectrometry (MS) and ion mobility technology have made to furthering our understanding of outer space. Find out more in our latest blog post.

History of Mass Spectrometry in Manchester – British Science Week

In honour of British Science week, we are going back to our roots to explore the rich heritage of MS in Manchester. Read on to discover the fascinating journey that has brought this technology to the modern age and the remarkable discoveries that have been made along the way…

Exploring Arctic biodiversity
with IMS

Today, the 22nd April, we celebrate Earth Day. Earth Day is a time to celebrate our planet’s rich biodiversity and highlight the importance of unique environments. In our latest blog post, Dr. Espen Hansen (pictured above) describes how the sustainable utilization of our planet’s biological resources is more important now than ever.

Identifying allergens in springtime treats

The decoration of eggs for springtime celebrations is an activity that can bring joy and life into a household. For many, it can conjure up memories of baskets full of sweet goodies and egg hunts through the woods in springtime. However, spring can bring with it a number of allergy symptoms

The Key to Your Heart: Valentine’s Treats and Sweets

Valentine’s Day is a time to celebrate romance and love, often by gifting that special someone with sweet treats to enjoy throughout the day. But have you ever wondered where this tradition of edible gifting came from and how it is changing in the modern age?

IMS and the safety of festive foods

With a global food supply chain opening up new opportunities for food fraud, and a spike in demand over the holidays, increasingly advanced analytical methods are required to ensure our food remains safe and authentic.

Choosing the right IMS instrument

So, you have decided that ion mobility spectrometry – mass spectrometry (IMS-MS) is a technique that you need to consider for your analytical repertoire.

An insight into IMS-MS imaging

Chemical imaging gives us the ability to provide direct insight into the localization of molecules within a sample.

Top 5 reasons to use IMS-MS

Mass spectrometry (MS) is a widely used analytical technique that measures the mass-to charge (m/z) ratio of ions.